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KMID : 0371319920430060812
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Journal of the Korean Surgical Society
1992 Volume.43 No. 6 p.812 ~ p.819
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Significance of Arterial Ketone Body Ratio in Hepatic Resection
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김홍진
윤성수/도병수/성석/송선교/심민철/권굉보/함희원
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Abstract
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Arterial ketone body ratio(AKBR) and Redox tolerance index(RTI) have been reported to represent hepatocyte energy state and function accurately. Therefore these tests have been frequently utilized for measurement of hepatic functional reserve
before
major hepatic resection.
In order to evaluate the value of AKBR and RTI in liver surgery authors performed the redox tolerance test to assess preoperative hepatic functional reserve and observed serial changes in AKBR during operation and the postoperative period in 45
hepatectomies, and analysed their results in relation to postoperative complications and mortality.
@ES The results are as follows;
@EN 1) RTI in cirrhotic liver patients was significantly lower than in noncirrhotic patients(p<0.05)
2) In five out of forty-five patients, RTI was below 0.5 and four of them died after major hepatectomy. All remaining forty-one patients with RTI above 0.5 survived.
3) AKBR during operation was below 0.4 in five patients, and four of them died due to postoperative liver failure.
4) In the four mortality cases, postoperative AKBR was not restored above 0.7. Howerer in all recovered cases, postoperative AKBR was restored above 0.7 immediately after hepatectomy.
From these results, we conclude that RTI based on redox theory has potential value in predicting posthepatectomy outcome and that the measurement of AKBR during operation and the postoperative period is important in the prognostic evaluation of
liver
surgery.
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KEYWORD
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